G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

Thies Ingwersen; Christian Linnenberg; Emanuela D'Acunto; Shabnam Temori; Irene Paolucci; David Wasilewski; Behnam Mohammadi; Johannes Kirchmair; Robert C Glen; Elena Miranda; Markus Glatzel; Giovanna Galliciotti

doi:10.1038/s41598-021-88090-1

G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

Thies Ingwersen, Christian Linnenberg, Emanuela D'Acunto, Shabnam Temori, Irene Paolucci, David Wasilewski, Behnam Mohammadi, Johannes Kirchmair, Robert C Glen, Elena Miranda, Markus Glatzel, Giovanna Galliciotti (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	8766
Number of pages	13
Journal	Scientific Reports
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41598-021-88090-1
Publication status	Published - 22 Apr 2021

Funding

MG was supported by DFG grant SFB877. EM was funded by the Pasteur Institute -Cenci Bolognetti Foundation (Italy) and Sapienza University of Rome (Italy).

Austrian Fields of Science 2012

106005 Bioinformatics
301207 Pharmaceutical chemistry

Keywords

TISSUE-PLASMINOGEN ACTIVATOR
FAMILIAL ENCEPHALOPATHY
Z ALPHA(1)-ANTITRYPSIN
INHIBITOR NEUROSERPIN
MUTANT NEUROSERPIN
POLYMERS
ACCUMULATION
DYSFUNCTION
PLASTICITY

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10.1038/s41598-021-88090-1Licence: CC BY 4.0

https://phaidra.univie.ac.at/o:1621464Licence: CC BY 4.0

Cite this

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title = "G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic",

keywords = "TISSUE-PLASMINOGEN ACTIVATOR, FAMILIAL ENCEPHALOPATHY, Z ALPHA(1)-ANTITRYPSIN, INHIBITOR NEUROSERPIN, MUTANT NEUROSERPIN, POLYMERS, ACCUMULATION, DYSFUNCTION, PLASTICITY",

author = "Thies Ingwersen and Christian Linnenberg and Emanuela D'Acunto and Shabnam Temori and Irene Paolucci and David Wasilewski and Behnam Mohammadi and Johannes Kirchmair and Glen, \{Robert C\} and Elena Miranda and Markus Glatzel and Giovanna Galliciotti",

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doi = "10.1038/s41598-021-88090-1",

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T1 - G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

AU - Ingwersen, Thies

AU - Linnenberg, Christian

AU - D'Acunto, Emanuela

AU - Temori, Shabnam

AU - Paolucci, Irene

AU - Wasilewski, David

AU - Mohammadi, Behnam

AU - Kirchmair, Johannes

AU - Glen, Robert C

AU - Miranda, Elena

AU - Glatzel, Markus

AU - Galliciotti, Giovanna

PY - 2021/4/22

Y1 - 2021/4/22

KW - TISSUE-PLASMINOGEN ACTIVATOR

KW - FAMILIAL ENCEPHALOPATHY

KW - Z ALPHA(1)-ANTITRYPSIN

KW - INHIBITOR NEUROSERPIN

KW - MUTANT NEUROSERPIN

KW - POLYMERS

KW - ACCUMULATION

KW - DYSFUNCTION

KW - PLASTICITY

UR - https://www.scopus.com/pages/publications/85104605840

U2 - 10.1038/s41598-021-88090-1

DO - 10.1038/s41598-021-88090-1

M3 - Article

C2 - 33888787

SN - 2045-2322

VL - 11

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 8766

ER -

G392E neuroserpin causing the dementia FENIB is secreted from cells but is not synaptotoxic

Funding

Austrian Fields of Science 2012

Keywords

Access to Document

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