GABA(A) receptor modulation by piperine and a non-TRPV1 activating derivative

Sophia Khom; Barbara Strommer; Angela Schöffmann; Juliane Hintersteiner; Igor Baburin; Thomas Erker; Thomas Schwarz; Christoph Schwarzer; Janine Zaugg; Matthias Hamburger; Steffen Hering

doi:10.1016/j.bcp.2013.04.017

GABA(A) receptor modulation by piperine and a non-TRPV1 activating derivative

Sophia Khom
, Barbara Strommer
, Angela Schöffmann
, Juliane Hintersteiner
, Igor Baburin
, Thomas Erker
, Thomas Schwarz
, Christoph Schwarzer
, Janine Zaugg
, Matthias Hamburger
, Steffen Hering (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	1827-1836
Number of pages	10
Journal	Biochemical Pharmacology
Volume	85
Issue number	12
DOIs	https://doi.org/10.1016/j.bcp.2013.04.017
Publication status	Published - 15 Jun 2013

Funding

This work was supported by the Austrian Science Fund (FWF P21241, TRP10, P22395 and the doctoral programme "Molecular drug targets" W1232 to S.H.) and the Swiss National Science Foundation (Project 31600-113109 to M.H.)

Austrian Fields of Science 2012

301206 Pharmacology
301406 Neuropharmacology
301207 Pharmaceutical chemistry

Keywords

GABA(A) receptors
TRPV1 channels
2-Microelectrode voltage clamp technique
Behavioural pharmacology
Piperine
POSITIVE ALLOSTERIC MODULATORS
VALERENIC ACID
XENOPUS OOCYTES
BENZODIAZEPINES
SUBTYPES
TRPV1
GABA(A)-RECEPTORS
IDENTIFICATION
SUBSTANCES
FLAVONOIDS

Access to Document

10.1016/j.bcp.2013.04.017Licence: CC BY-NC-SA 3.0

Cite this

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title = "GABA(A) receptor modulation by piperine and a non-TRPV1 activating derivative",

keywords = "GABA(A) receptors, TRPV1 channels, 2-Microelectrode voltage clamp technique, Behavioural pharmacology, Piperine, POSITIVE ALLOSTERIC MODULATORS, VALERENIC ACID, XENOPUS OOCYTES, BENZODIAZEPINES, SUBTYPES, TRPV1, GABA(A)-RECEPTORS, IDENTIFICATION, SUBSTANCES, FLAVONOIDS",

author = "Sophia Khom and Barbara Strommer and Angela Sch{\"o}ffmann and Juliane Hintersteiner and Igor Baburin and Thomas Erker and Thomas Schwarz and Christoph Schwarzer and Janine Zaugg and Matthias Hamburger and Steffen Hering",

year = "2013",

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doi = "10.1016/j.bcp.2013.04.017",

language = "English",

volume = "85",

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T1 - GABA(A) receptor modulation by piperine and a non-TRPV1 activating derivative

AU - Khom, Sophia

AU - Strommer, Barbara

AU - Schöffmann, Angela

AU - Hintersteiner, Juliane

AU - Baburin, Igor

AU - Erker, Thomas

AU - Schwarz, Thomas

AU - Schwarzer, Christoph

AU - Zaugg, Janine

AU - Hamburger, Matthias

AU - Hering, Steffen

PY - 2013/6/15

Y1 - 2013/6/15

KW - GABA(A) receptors

KW - TRPV1 channels

KW - 2-Microelectrode voltage clamp technique

KW - Behavioural pharmacology

KW - Piperine

KW - POSITIVE ALLOSTERIC MODULATORS

KW - VALERENIC ACID

KW - XENOPUS OOCYTES

KW - BENZODIAZEPINES

KW - SUBTYPES

KW - TRPV1

KW - GABA(A)-RECEPTORS

KW - IDENTIFICATION

KW - SUBSTANCES

KW - FLAVONOIDS

U2 - 10.1016/j.bcp.2013.04.017

DO - 10.1016/j.bcp.2013.04.017

M3 - Article

SN - 0006-2952

VL - 85

SP - 1827

EP - 1836

JO - Biochemical Pharmacology

JF - Biochemical Pharmacology

IS - 12

ER -