Gas-Phase Formation of Large Neutral Alkaline-Earth Metal Tryptophan Complexes

Markus Marksteiner, Philipp Haslinger, Hendrik Ulbricht, Michele Sclafani, Harald Oberhofer, Christoph Dellago, Markus Arndt

Publications: Contribution to journalArticlePeer Reviewed

Abstract

We report on the first observation of isolated large neutral metal amino acid complexes such as Trp n Me k , with Me = Ca, Ba, Sr, cluster combinations covering n = 1–33, k = 0..2 and masses beyond 6500 u. The cluster beam is generated using UV laser desorption from a mixed powder of alkaline-earth metal salts and tryptophan inside a cluster mixing channel. The particles are detected using VUV photoionization followed by time-of-flight mass spectroscopy. The enhanced stability of metal amino acid clusters over pure amino acid clusters is substantiated in molecular dynamics simulations by determining the gain in binding energy related to the inclusion of the metal atoms.
Original languageEnglish
Pages (from-to)1021-1026
Number of pages6
JournalJournal of the American Society for Mass Spectrometry
Volume19
Issue number7
DOIs
Publication statusPublished - 2008

Austrian Fields of Science 2012

  • 103026 Quantum optics

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