TY - JOUR
T1 - Gas-Phase Formation of Large Neutral Alkaline-Earth Metal Tryptophan Complexes
AU - Marksteiner, Markus
AU - Haslinger, Philipp
AU - Ulbricht, Hendrik
AU - Sclafani, Michele
AU - Oberhofer, Harald
AU - Dellago, Christoph
AU - Arndt, Markus
N1 - ***<REP_Import><OA_Full_2012>127112.28</OA_Full_2012></REP_Import>***
PY - 2008
Y1 - 2008
N2 - We report on the first observation of isolated large neutral metal amino acid complexes such as Trp n Me k , with Me = Ca, Ba, Sr, cluster combinations covering n = 1–33, k = 0..2 and masses beyond 6500 u. The cluster beam is generated using UV laser desorption from a mixed powder of alkaline-earth metal salts and tryptophan inside a cluster mixing channel. The particles are detected using VUV photoionization followed by time-of-flight mass spectroscopy. The enhanced stability of metal amino acid clusters over pure amino acid clusters is substantiated in molecular dynamics simulations by determining the gain in binding energy related to the inclusion of the metal atoms.
AB - We report on the first observation of isolated large neutral metal amino acid complexes such as Trp n Me k , with Me = Ca, Ba, Sr, cluster combinations covering n = 1–33, k = 0..2 and masses beyond 6500 u. The cluster beam is generated using UV laser desorption from a mixed powder of alkaline-earth metal salts and tryptophan inside a cluster mixing channel. The particles are detected using VUV photoionization followed by time-of-flight mass spectroscopy. The enhanced stability of metal amino acid clusters over pure amino acid clusters is substantiated in molecular dynamics simulations by determining the gain in binding energy related to the inclusion of the metal atoms.
U2 - 10.1016/j.jasms.2008.04.028
DO - 10.1016/j.jasms.2008.04.028
M3 - Article
SN - 1044-0305
VL - 19
SP - 1021
EP - 1026
JO - Journal of the American Society for Mass Spectrometry
JF - Journal of the American Society for Mass Spectrometry
IS - 7
ER -