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GermOnline, a cross-species community knowledgebase on germ cell differentiation

  • Christa Wiederkehr
  • , R Basavaraj
  • , C Sarrauste de Menthiere
  • , Leandro Hermida
  • , R. Koch
  • , Ulrich Schlecht
  • , Angelika Amon
  • , Sophie Brachat
  • , Michael Breitenbach
  • , Peter Briza
  • , S Caburet
  • , Maria Cherry
  • , Robert Davis
  • , Adam M. Deutschbauer
  • , Hugh G. Dickinson
  • , Teodora Pene Dumitrescu
  • , Marc Fellous
  • , A Goldman
  • , J. Anton Grootegoed
  • , R. Scott Hawley
  • R Ishii, Bernard Jegou, Randal J. Kaufman, Franz Klein, N Lamb, Bernard Maro, Kim Nasmyth, Alain Nicolas, Terry L. Orr-Weaver, Peter Philippsen, Charles P. Pineau, Kirsten P Rabitsch, Valerie Reinke, Henk P. Roest, William S. Saunders, Martin Schröder, Tim Schedl, Michel Siep, Anne M. Villeneuve, Debra J. Wolgemuth, M Yamamoto, Denise Zickler, Rochelle Easton Esposito, Michael Primig

Publications: Contribution to journalArticlePeer Reviewed

Abstract

GermOnline provides information and microarray expression data for genes involved in mitosis and meiosis, gamete formation and germ line development across species. The database has been developed, and is being curated and updated, by life scientists in cooperation with bioinformaticists. Information is contributed through an online form using free text, images and the controlled vocabulary developed by the GeneOntology Consortium. Authors provide up to three references in support of their contribution. The database is governed by an international board of scientists to ensure a standardized data format and the highest quality of GermOnline's information content. Release 2.0 provides exclusive access to microarray expression data from Saccharomyces cerevisiae and Rattus norvegicus, as well as curated information on ~700 genes from various organisms. The locus report pages include links to external databases that contain relevant annotation, microarray expression and proteome data. Conversely, the Saccharomyces Genome Database (SGD), S.cerevisiae GeneDB and Swiss-Prot link to the budding yeast section of GermOnline from their respective locus pages. GermOnline, a fully operational prototype subject-oriented knowledgebase designed for community annotation and array data visualization, is accessible at http://www.germonline.org. The target audience includes researchers who work on mitotic cell division, meiosis, gametogenesis, germ line development, human reproductive health and comparative genomics.
Original languageEnglish
Pages (from-to)560-567
Number of pages8
JournalNucleic Acids Research
Volume32
Issue numberDATABASE I
Publication statusPublished - 2004

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

  • 1060 Biology

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