Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

Jana Gerstmeier; Julia Seegers; Finja Witt; Birgit Waltenberger; Veronika Temml; Judith M Rollinger; Hermann Stuppner; Andreas Koeberle; Daniela Schuster; Oliver Werz

doi:10.3389/fphar.2019.00797

Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

Jana Gerstmeier
, Julia Seegers
, Finja Witt
, Birgit Waltenberger
, Veronika Temml
, Judith M Rollinger
, Hermann Stuppner
, Andreas Koeberle
, Daniela Schuster
, Oliver Werz

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	797
Number of pages	15
Journal	Frontiers in Pharmacology
Volume	10
DOIs	https://doi.org/10.3389/fphar.2019.00797
Publication status	Published - 17 Jul 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

104015 Organic chemistry
301208 Pharmaceutical technology
301206 Pharmacology
301204 Pharmacognosy

Keywords

5-LIPOXYGENASE INHIBITORS
5-lipoxygenase
ANTIINFLAMMATORY DRUGS
BILOBA L
CELLS
CHALLENGES
CYTOTOXICITY
LEUKOTRIENE BIOSYNTHESIS
PROSTAGLANDIN E-2 SYNTHASE-1
RESOLUTION
SUMOYLATION
cyclooxygenase
ginkgolic acid
lipid mediator
microsomal prostaglandin E-2 synthase-1
multi-target inhibitor
microsomal prostaglandin E2 synthase-1

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10.3389/fphar.2019.00797Licence: CC BY 4.0

https://phaidra.univie.ac.at/o:1146404Licence: CC BY 4.0

Cite this

@article{b7a14edf359e478982755bb149528417,

title = "Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis",

keywords = "5-LIPOXYGENASE INHIBITORS, 5-lipoxygenase, ANTIINFLAMMATORY DRUGS, BILOBA L, CELLS, CHALLENGES, CYTOTOXICITY, LEUKOTRIENE BIOSYNTHESIS, PROSTAGLANDIN E-2 SYNTHASE-1, RESOLUTION, SUMOYLATION, cyclooxygenase, ginkgolic acid, lipid mediator, microsomal prostaglandin E-2 synthase-1, multi-target inhibitor, microsomal prostaglandin E2 synthase-1",

author = "Jana Gerstmeier and Julia Seegers and Finja Witt and Birgit Waltenberger and Veronika Temml and Rollinger, \{Judith M\} and Hermann Stuppner and Andreas Koeberle and Daniela Schuster and Oliver Werz",

note = "Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2019 Gerstmeier, Seegers, Witt, Waltenberger, Temml, Rollinger, Stuppner, Koeberle, Schuster and Werz.",

year = "2019",

month = jul,

day = "17",

doi = "10.3389/fphar.2019.00797",

language = "English",

volume = "10",

journal = "Frontiers in Pharmacology",

issn = "1663-9812",

publisher = "FRONTIERS MEDIA SA",

}

TY - JOUR

T1 - Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

AU - Gerstmeier, Jana

AU - Seegers, Julia

AU - Witt, Finja

AU - Waltenberger, Birgit

AU - Temml, Veronika

AU - Rollinger, Judith M

AU - Stuppner, Hermann

AU - Koeberle, Andreas

AU - Schuster, Daniela

AU - Werz, Oliver

PY - 2019/7/17

Y1 - 2019/7/17

KW - 5-LIPOXYGENASE INHIBITORS

KW - 5-lipoxygenase

KW - ANTIINFLAMMATORY DRUGS

KW - BILOBA L

KW - CELLS

KW - CHALLENGES

KW - CYTOTOXICITY

KW - LEUKOTRIENE BIOSYNTHESIS

KW - PROSTAGLANDIN E-2 SYNTHASE-1

KW - RESOLUTION

KW - SUMOYLATION

KW - cyclooxygenase

KW - ginkgolic acid

KW - lipid mediator

KW - microsomal prostaglandin E-2 synthase-1

KW - multi-target inhibitor

KW - microsomal prostaglandin E2 synthase-1

UR - https://www.scopus.com/pages/publications/85083860887

U2 - 10.3389/fphar.2019.00797

DO - 10.3389/fphar.2019.00797

M3 - Article

C2 - 31379572

SN - 1663-9812

VL - 10

JO - Frontiers in Pharmacology

JF - Frontiers in Pharmacology

M1 - 797

ER -

Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

UN SDGs

Austrian Fields of Science 2012

Keywords

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