Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

Laetitia Moreno Y. Banuls; Adriana Katz; Walter Miklos; Alessio Cimmino; Daniel M. Tal; Elena Ainbinder; Martin Zehl; Ernst Urban; Antonio Evidente; Brigitte Kopp; Walter Berger; Olivier Feron; Steven Karlish; Robert Kiss

doi:10.1186/1476-4598-12-33

Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na⁺/K⁺-ATPase

Laetitia Moreno Y. Banuls
, Adriana Katz
, Walter Miklos
, Alessio Cimmino
, Daniel M. Tal
, Elena Ainbinder
, Martin Zehl
, Ernst Urban
, Antonio Evidente
, Brigitte Kopp
, Walter Berger
, Olivier Feron
, Steven Karlish
, Robert Kiss (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	33
Number of pages	14
Journal	Molecular Cancer
Volume	12
DOIs	https://doi.org/10.1186/1476-4598-12-33
Publication status	Published - 26 Apr 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry
301204 Pharmacognosy

Keywords

Cardiotonic steroids
Cardenolides
Bufadienolides
Cancer
Glycoside / aglycone forms
Lactate release - oxygen consumption
CARDIAC-GLYCOSIDES
SODIUM-PUMP
CARDIOTONIC STEROIDS
GENE-EXPRESSION
DRUG-DISCOVERY
UP-REGULATION
LUNG CANCERS
OUABAIN
CARCINOMA
DEATH

Access to Document

10.1186/1476-4598-12-33Licence: Other

http://phaidra.univie.ac.at/o:502678Licence: Other

Cite this

Banuls, L. M. Y., Katz, A., Miklos, W., Cimmino, A., Tal, D. M., Ainbinder, E., Zehl, M., Urban, E., Evidente, A., Kopp, B., Berger, W., Feron, O., Karlish, S., & Kiss, R. (2013). Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na⁺/K⁺-ATPase. Molecular Cancer, 12, Article 33. https://doi.org/10.1186/1476-4598-12-33

@article{cb97f339c8af4d2199c0d5bcd92e90b4,

title = "Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase",

keywords = "Cardiotonic steroids, Cardenolides, Bufadienolides, Cancer, Glycoside / aglycone forms, Lactate release - oxygen consumption, CARDIAC-GLYCOSIDES, SODIUM-PUMP, CARDIOTONIC STEROIDS, GENE-EXPRESSION, DRUG-DISCOVERY, UP-REGULATION, LUNG CANCERS, OUABAIN, CARCINOMA, DEATH",

author = "Banuls, \{Laetitia Moreno Y.\} and Adriana Katz and Walter Miklos and Alessio Cimmino and Tal, \{Daniel M.\} and Elena Ainbinder and Martin Zehl and Ernst Urban and Antonio Evidente and Brigitte Kopp and Walter Berger and Olivier Feron and Steven Karlish and Robert Kiss",

year = "2013",

month = apr,

day = "26",

doi = "10.1186/1476-4598-12-33",

language = "English",

volume = "12",

journal = "Molecular Cancer",

issn = "1476-4598",

}

Banuls, LMY, Katz, A, Miklos, W, Cimmino, A, Tal, DM, Ainbinder, E, Zehl, M, Urban, E, Evidente, A, Kopp, B, Berger, W, Feron, O, Karlish, S & Kiss, R 2013, 'Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na⁺/K⁺-ATPase', Molecular Cancer, vol. 12, 33. https://doi.org/10.1186/1476-4598-12-33

TY - JOUR

T1 - Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase

AU - Banuls, Laetitia Moreno Y.

AU - Katz, Adriana

AU - Miklos, Walter

AU - Cimmino, Alessio

AU - Tal, Daniel M.

AU - Ainbinder, Elena

AU - Zehl, Martin

AU - Urban, Ernst

AU - Evidente, Antonio

AU - Kopp, Brigitte

AU - Berger, Walter

AU - Feron, Olivier

AU - Karlish, Steven

AU - Kiss, Robert

PY - 2013/4/26

Y1 - 2013/4/26

KW - Cardiotonic steroids

KW - Cardenolides

KW - Bufadienolides

KW - Cancer

KW - Glycoside / aglycone forms

KW - Lactate release - oxygen consumption

KW - CARDIAC-GLYCOSIDES

KW - SODIUM-PUMP

KW - CARDIOTONIC STEROIDS

KW - GENE-EXPRESSION

KW - DRUG-DISCOVERY

KW - UP-REGULATION

KW - LUNG CANCERS

KW - OUABAIN

KW - CARCINOMA

KW - DEATH

U2 - 10.1186/1476-4598-12-33

DO - 10.1186/1476-4598-12-33

M3 - Article

SN - 1476-4598

VL - 12

JO - Molecular Cancer

JF - Molecular Cancer

M1 - 33

ER -