High-Quality Dataset of Protein-Bound Ligand Conformations and Its Application to Benchmarking Conformer Ensemble Generators

  • Nils-Ole Friedrich
  • , Agnes Meyder
  • , Christina de Bruyn Kops
  • , Kai Sommer
  • , Florian Flachsenberg
  • , Matthias Rarey
  • , Johannes Kirchmair (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)529–539
Number of pages11
JournalJournal of Chemical Information and Modeling
Volume57
Issue number3
DOIs
Publication statusPublished - Mar 2017
Externally publishedYes

Austrian Fields of Science 2012

  • 106005 Bioinformatics
  • 301207 Pharmaceutical chemistry

Keywords

  • 3D CONFORMATION
  • CAMBRIDGE STRUCTURAL DATABASE
  • DATA-BANK
  • DISTANCE-GEOMETRY
  • DRUG DISCOVERY
  • ELECTRON-DENSITY
  • FORCE-FIELD
  • MOLECULAR-MECHANICS OPTIMIZATION
  • TEST SET
  • VALIDATION

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