Hydrogen-Bonding Patterns of Minor Groove-Binder-DNA Complexes Reveal Criteria for Discovery of New Scaffolds

Gudrun M. Spitzer; Bernd Wellenzohn; Patrick Markt; Johannes Kirchmair; Thierry Langer; Klaus R. Liedl

doi:10.1021/ci800455f

Hydrogen-Bonding Patterns of Minor Groove-Binder-DNA Complexes Reveal Criteria for Discovery of New Scaffolds

Gudrun M. Spitzer, Bernd Wellenzohn, Patrick Markt, Johannes Kirchmair, Thierry Langer, Klaus R. Liedl

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	1063-1069
Number of pages	7
Journal	Journal of Chemical Information and Modeling
Volume	49
Issue number	4
DOIs	https://doi.org/10.1021/ci800455f
Publication status	Published - Apr 2009
Externally published	Yes

Funding

This work was supported by the Austrian Science Fund (Project P19756).

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Keywords

GRAM-POSITIVE BACTERIA
VAN-DER-WAALS
HAIRPIN POLYAMIDES
BINDING LIGANDS
NUCLEIC-ACIDS
GENE-EXPRESSION
BASE-PAIRS
ALTERNATIVE HETEROCYCLES
IMIDAZOLE POLYAMIDES
ANTIMICROBIAL AGENTS

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10.1021/ci800455f

Cite this

@article{719215d506bc41aba4011395e0d23209,

title = "Hydrogen-Bonding Patterns of Minor Groove-Binder-DNA Complexes Reveal Criteria for Discovery of New Scaffolds",

keywords = "GRAM-POSITIVE BACTERIA, VAN-DER-WAALS, HAIRPIN POLYAMIDES, BINDING LIGANDS, NUCLEIC-ACIDS, GENE-EXPRESSION, BASE-PAIRS, ALTERNATIVE HETEROCYCLES, IMIDAZOLE POLYAMIDES, ANTIMICROBIAL AGENTS",

author = "Spitzer, \{Gudrun M.\} and Bernd Wellenzohn and Patrick Markt and Johannes Kirchmair and Thierry Langer and Liedl, \{Klaus R.\}",

year = "2009",

month = apr,

doi = "10.1021/ci800455f",

language = "English",

volume = "49",

pages = "1063--1069",

journal = "Journal of Chemical Information and Modeling",

issn = "1549-9596",

publisher = "AMER CHEMICAL SOC",

number = "4",

}

TY - JOUR

T1 - Hydrogen-Bonding Patterns of Minor Groove-Binder-DNA Complexes Reveal Criteria for Discovery of New Scaffolds

AU - Spitzer, Gudrun M.

AU - Wellenzohn, Bernd

AU - Markt, Patrick

AU - Kirchmair, Johannes

AU - Langer, Thierry

AU - Liedl, Klaus R.

PY - 2009/4

Y1 - 2009/4

KW - GRAM-POSITIVE BACTERIA

KW - VAN-DER-WAALS

KW - HAIRPIN POLYAMIDES

KW - BINDING LIGANDS

KW - NUCLEIC-ACIDS

KW - GENE-EXPRESSION

KW - BASE-PAIRS

KW - ALTERNATIVE HETEROCYCLES

KW - IMIDAZOLE POLYAMIDES

KW - ANTIMICROBIAL AGENTS

U2 - 10.1021/ci800455f

DO - 10.1021/ci800455f

M3 - Article

SN - 1549-9596

VL - 49

SP - 1063

EP - 1069

JO - Journal of Chemical Information and Modeling

JF - Journal of Chemical Information and Modeling

IS - 4

ER -

Hydrogen-Bonding Patterns of Minor Groove-Binder-DNA Complexes Reveal Criteria for Discovery of New Scaffolds

Funding

Austrian Fields of Science 2012

Keywords

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