IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala

Reesha R. Patel; Sophia Khom; Michael Q. Steinman; Florence P. Varodayan; William B. Kiosses; David M. Hedges; Roman Vlkolinsky; Tali Nadav; Ilham Polis; Michal Bajo; Amanda J. Roberts; Marisa Roberto

doi:10.1016/j.bbi.2018.10.009

IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala

Reesha R. Patel, Sophia Khom, Michael Q. Steinman, Florence P. Varodayan, William B. Kiosses, David M. Hedges, Roman Vlkolinsky, Tali Nadav, Ilham Polis, Michal Bajo, Amanda J. Roberts, Marisa Roberto

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	208-219
Number of pages	12
Journal	Brain, behavior, and immunity
Volume	75
DOIs	https://doi.org/10.1016/j.bbi.2018.10.009
Publication status	Published - Jan 2019
Externally published	Yes

Funding

We would like to thank Dr. Kazantzis from the Metabolic Core at Scripps Research Institute (Jupiter, Florida) for conducting the Luminex assay. This work was supported by National Institute of Alcohol Abuse and Alcoholism grants INIA-Neuroimmune U01 AA013498 , F32 AA026865 , AA015566 , AA021491 , AA006420 , AA017447 , T32 AA007456 , and K99/R00 AA025408 and the Austrian Science Fund FWF-J-3942. The authors declare no conflict of interest. This is Scripps manuscript number 29721.

Austrian Fields of Science 2012

301406 Neuropharmacology

Keywords

Alcohol
CeA
Ethanol dependence
GABA
IL-1β
CYTOKINES
MICROGLIAL ACTIVATION
GABAERGIC TRANSMISSION
IL-1
INTERLEUKIN-1 RECEPTOR ANTAGONIST
SYNAPTIC-TRANSMISSION
IL-1 beta
ALCOHOL-INDUCED NEUROINFLAMMATION
CORTICOTROPIN-RELEASING-FACTOR
ACCESSORY PROTEIN
BRAIN

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10.1016/j.bbi.2018.10.009

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Patel, R. R., Khom, S., Steinman, M. Q., Varodayan, F. P., Kiosses, W. B., Hedges, D. M., Vlkolinsky, R., Nadav, T., Polis, I., Bajo, M., Roberts, A. J., & Roberto, M. (2019). IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala. Brain, behavior, and immunity, 75, 208-219. https://doi.org/10.1016/j.bbi.2018.10.009

@article{c11e64ae88cb45a3a65b949c114bdaae,

title = "IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala",

keywords = "Alcohol, CeA, Ethanol dependence, GABA, IL-1β, CYTOKINES, MICROGLIAL ACTIVATION, GABAERGIC TRANSMISSION, IL-1, INTERLEUKIN-1 RECEPTOR ANTAGONIST, SYNAPTIC-TRANSMISSION, IL-1 beta, ALCOHOL-INDUCED NEUROINFLAMMATION, CORTICOTROPIN-RELEASING-FACTOR, ACCESSORY PROTEIN, BRAIN",

author = "Patel, \{Reesha R.\} and Sophia Khom and Steinman, \{Michael Q.\} and Varodayan, \{Florence P.\} and Kiosses, \{William B.\} and Hedges, \{David M.\} and Roman Vlkolinsky and Tali Nadav and Ilham Polis and Michal Bajo and Roberts, \{Amanda J.\} and Marisa Roberto",

note = "Funding Information: We would like to thank Dr. Kazantzis from the Metabolic Core at Scripps Research Institute (Jupiter, Florida) for conducting the Luminex assay. This work was supported by National Institute of Alcohol Abuse and Alcoholism grants INIA-Neuroimmune U01 AA013498 , F32 AA026865 , AA015566 , AA021491 , AA006420 , AA017447 , T32 AA007456 , and K99/R00 AA025408 and the Austrian Science Fund FWF-J-3942. The authors declare no conflict of interest. This is Scripps manuscript number 29721. Publisher Copyright: {\textcopyright} 2018 Elsevier Inc. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",

year = "2019",

month = jan,

doi = "10.1016/j.bbi.2018.10.009",

language = "English",

volume = "75",

pages = "208--219",

journal = "Brain, behavior, and immunity",

issn = "0889-1591",

publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",

}

TY - JOUR

T1 - IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala

AU - Patel, Reesha R.

AU - Khom, Sophia

AU - Steinman, Michael Q.

AU - Varodayan, Florence P.

AU - Kiosses, William B.

AU - Hedges, David M.

AU - Vlkolinsky, Roman

AU - Nadav, Tali

AU - Polis, Ilham

AU - Bajo, Michal

AU - Roberts, Amanda J.

AU - Roberto, Marisa

N1 - Funding Information: We would like to thank Dr. Kazantzis from the Metabolic Core at Scripps Research Institute (Jupiter, Florida) for conducting the Luminex assay. This work was supported by National Institute of Alcohol Abuse and Alcoholism grants INIA-Neuroimmune U01 AA013498 , F32 AA026865 , AA015566 , AA021491 , AA006420 , AA017447 , T32 AA007456 , and K99/R00 AA025408 and the Austrian Science Fund FWF-J-3942. The authors declare no conflict of interest. This is Scripps manuscript number 29721. Publisher Copyright: © 2018 Elsevier Inc. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/1

Y1 - 2019/1

KW - Alcohol

KW - CeA

KW - Ethanol dependence

KW - GABA

KW - IL-1β

KW - CYTOKINES

KW - MICROGLIAL ACTIVATION

KW - GABAERGIC TRANSMISSION

KW - IL-1

KW - INTERLEUKIN-1 RECEPTOR ANTAGONIST

KW - SYNAPTIC-TRANSMISSION

KW - IL-1 beta

KW - ALCOHOL-INDUCED NEUROINFLAMMATION

KW - CORTICOTROPIN-RELEASING-FACTOR

KW - ACCESSORY PROTEIN

KW - BRAIN

UR - https://www.scopus.com/pages/publications/85055744820

U2 - 10.1016/j.bbi.2018.10.009

DO - 10.1016/j.bbi.2018.10.009

M3 - Article

C2 - 30791967

AN - SCOPUS:85055744820

SN - 0889-1591

VL - 75

SP - 208

EP - 219

JO - Brain, behavior, and immunity

JF - Brain, behavior, and immunity

ER -

IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala

Funding

Austrian Fields of Science 2012

Keywords

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