Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei

Trygve Brautaset, Havard Sletta, Aina Nedal, Sven Even F. Borgos, Kristin F. Degnes, Ingrid Bakke, Olga Volokhan, Olga N. Sekurova, Ivan D. Treshalin, Elena P. Mirchink, Alexander Dikiy, Trond E. Ellingsen, Sergey B. Zotchev

    Publications: Contribution to journalArticlePeer Reviewed

    Original languageEnglish
    Pages (from-to)1198-1206
    Number of pages9
    JournalChemistry & Biology
    Volume15
    Issue number11
    DOIs
    Publication statusPublished - 24 Nov 2008

    Austrian Fields of Science 2012

    • 106022 Microbiology
    • 106013 Genetics
    • 104013 Natural product chemistry
    • 301204 Pharmacognosy

    Keywords

    • AMPHOTERICIN-B
    • ANTIBIOTIC NYSTATIN
    • FUNGAL-INFECTIONS
    • POLYKETIDE SYNTHASE
    • ATCC 11455
    • CLUSTER
    • DERIVATIVES
    • MYCOSAMINE
    • MANAGEMENT
    • ATCC-11455

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