In-depth interrogation of protein thermal unfolding data with MoltenProt

Vadim Kotov, Georg Mlynek, Oliver Vesper, Marina Pletzer, Jiri Wald, Celso M. Teixeira-Duarte, Herve Celia, Maria Garcia-Alai, Stephan Nussberger, Susan K. Buchanan, João H. Morais-Cabral, Christian Loew, Kristina Djinovic-Carugo, Thomas C. Marlovits (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)201-217
Number of pages17
JournalProtein Science
Volume30
Issue number1
Early online date2 Nov 2020
DOIs
Publication statusPublished - Jan 2021

Austrian Fields of Science 2012

  • 106002 Biochemistry
  • 301304 Medical biology
  • 106041 Structural biology

Keywords

  • buffer optimization
  • high-throughput screening
  • melting temperature
  • MoltenProt
  • NanoDSF
  • protein unfolding
  • thermostability
  • CRYSTALLIZATION
  • STABILITY OPTIMIZATION
  • STABILIZATION
  • Z-DISC
  • high&#8208
  • DIFFERENTIAL SCANNING CALORIMETRY
  • FILAMIN-BINDING
  • THERMODYNAMICS
  • FLUORESCENCE
  • ACTININ-BINDING
  • MEMBRANE-PROTEINS
  • throughput screening

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