In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes

Theresa Balber; Katarina Bencurova; Florian Wolfgang Kiefer; Oana Cristina Kulterer; Eva-Maria Klebermass; Gerda Egger; Loan Tran; Karl-Heinz Wagner; Helmut Viernstein; Katharina Pallitsch; Helmut Spreitzer; Marcus Hacker; Wolfgang Wadsak; Markus Mitterhauser; Cecile Philippe

doi:10.3389/fendo.2019.00324

In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes

Theresa Balber
, Katarina Bencurova
, Florian Wolfgang Kiefer
, Oana Cristina Kulterer
, Eva-Maria Klebermass
, Gerda Egger
, Loan Tran
, Karl-Heinz Wagner
, Helmut Viernstein
, Katharina Pallitsch
, Helmut Spreitzer
, Marcus Hacker
, Wolfgang Wadsak
, Markus Mitterhauser (Corresponding author)
, Cecile Philippe

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	324
Journal	Frontiers in Endocrinology
Volume	10
DOIs	https://doi.org/10.3389/fendo.2019.00324
Publication status	Published - 11 Jun 2019

Funding

The authors want to thank the production team of the General Hospital in Vienna for providing [<SUP>18</SUP>F] FDG. Verena Pichler, Thomas Zenz, and Andreas Krcal are gratefully acknowledged for their organizational and technical support. Madeleine Kuroll is gratefully acknowledged for her support in qPCR. We thank Stefanie Bugayong for her skillful help with the animals. The authors thank Mohammad Reza Kamali Sarvestani for his participation in binding experiments. This study was conducted with the support of the Medical Imaging Cluster (MIC), Medical University of Vienna.

Austrian Fields of Science 2012

302014 Endocrinology
301208 Pharmaceutical technology

Keywords

melanin-concentrating hormone receptor 1
MCHR1
brown adipocytes
BAT
adrenergic beta-3 receptor
[F-18]FE@SNAP
[C-11]SNAP-7941
PET
MELANIN-CONCENTRATING HORMONE
1ST PET-TRACER
ADIPOSE-TISSUE
VIVO EVALUATION
RECEPTOR
FAT
THERMOGENESIS
METABOLISM
MECHANISM
PATHWAYS
[ C]SNAP-7941
Melanin-concentrating hormone receptor 1
[ F]FENAP
Brown adipocytes
Adrenergic beta-3 receptor

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3389/fendo.2019.00324Licence: CC BY 4.0

https://phaidra.univie.ac.at/o:1144836Licence: CC BY 4.0

Cite this

Balber, T., Bencurova, K., Kiefer, F. W., Kulterer, O. C., Klebermass, E.-M., Egger, G., Tran, L., Wagner, K.-H., Viernstein, H., Pallitsch, K., Spreitzer, H., Hacker, M., Wadsak, W., Mitterhauser, M., & Philippe, C. (2019). In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes. Frontiers in Endocrinology, 10, Article 324. https://doi.org/10.3389/fendo.2019.00324

@article{e0419bd6a69a496f8e087e659b84f098,

title = "In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes",

keywords = "melanin-concentrating hormone receptor 1, MCHR1, brown adipocytes, BAT, adrenergic beta-3 receptor, [F-18]FE@SNAP, [C-11]SNAP-7941, PET, MELANIN-CONCENTRATING HORMONE, 1ST PET-TRACER, ADIPOSE-TISSUE, VIVO EVALUATION, RECEPTOR, FAT, THERMOGENESIS, METABOLISM, MECHANISM, PATHWAYS, [ C]SNAP-7941, Melanin-concentrating hormone receptor 1, [ F]FENAP, Brown adipocytes, Adrenergic beta-3 receptor",

author = "Theresa Balber and Katarina Bencurova and Kiefer, \{Florian Wolfgang\} and Kulterer, \{Oana Cristina\} and Eva-Maria Klebermass and Gerda Egger and Loan Tran and Karl-Heinz Wagner and Helmut Viernstein and Katharina Pallitsch and Helmut Spreitzer and Marcus Hacker and Wolfgang Wadsak and Markus Mitterhauser and Cecile Philippe",

note = "Publisher Copyright: Copyright {\textcopyright} 2019 Balber, Ben{\v c}urov{\'a}, Kiefer, Kulterer, Klebermass, Egger, Tran, Wagner, Viernstein, Pallitsch, Spreitzer, Hacker, Wadsak, Mitterhauser and Philippe.",

year = "2019",

month = jun,

day = "11",

doi = "10.3389/fendo.2019.00324",

language = "English",

volume = "10",

journal = "Frontiers in Endocrinology",

issn = "1664-2392",

publisher = "FRONTIERS MEDIA SA",

}

Balber, T, Bencurova, K, Kiefer, FW, Kulterer, OC, Klebermass, E-M, Egger, G, Tran, L, Wagner, K-H , Viernstein, H , Pallitsch, K, Spreitzer, H, Hacker, M, Wadsak, W, Mitterhauser, M & Philippe, C 2019, 'In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes', Frontiers in Endocrinology, vol. 10, 324. https://doi.org/10.3389/fendo.2019.00324

TY - JOUR

T1 - In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes

AU - Balber, Theresa

AU - Bencurova, Katarina

AU - Kiefer, Florian Wolfgang

AU - Kulterer, Oana Cristina

AU - Klebermass, Eva-Maria

AU - Egger, Gerda

AU - Tran, Loan

AU - Wagner, Karl-Heinz

AU - Viernstein, Helmut

AU - Pallitsch, Katharina

AU - Spreitzer, Helmut

AU - Hacker, Marcus

AU - Wadsak, Wolfgang

AU - Mitterhauser, Markus

AU - Philippe, Cecile

PY - 2019/6/11

Y1 - 2019/6/11

KW - melanin-concentrating hormone receptor 1

KW - MCHR1

KW - brown adipocytes

KW - BAT

KW - adrenergic beta-3 receptor

KW - [F-18]FE@SNAP

KW - [C-11]SNAP-7941

KW - PET

KW - MELANIN-CONCENTRATING HORMONE

KW - 1ST PET-TRACER

KW - ADIPOSE-TISSUE

KW - VIVO EVALUATION

KW - RECEPTOR

KW - FAT

KW - THERMOGENESIS

KW - METABOLISM

KW - MECHANISM

KW - PATHWAYS

KW - [ C]SNAP-7941

KW - Melanin-concentrating hormone receptor 1

KW - [ F]FENAP

KW - Brown adipocytes

KW - Adrenergic beta-3 receptor

UR - https://www.scopus.com/pages/publications/85068971019

U2 - 10.3389/fendo.2019.00324

DO - 10.3389/fendo.2019.00324

M3 - Article

SN - 1664-2392

VL - 10

JO - Frontiers in Endocrinology

JF - Frontiers in Endocrinology

M1 - 324

ER -

In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes

Funding

Austrian Fields of Science 2012

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this