Abstract
Sub-aerial parts of Chaerophyllum aureum L. yielded two polyacetylenes, falcarinol (1), falcarindiol (2), three lignans, namely nemerosin (3), deoxypodorhizone (4), deoxypodo-phyllotoxin (5), two phenylpropanoids, 1′-hydroxymyristicin (6) and its angeloyl ester (7). Compounds 6 and 7 were isolated for the first time from plant material and their structures were elucidated by means of extensive 1- and 2-dimensional NMR spectroscopy and high resolution mass spectrometry. In bioautographic tests on TLC plates the dichloromethane extract showed a significant antimicrobial activity. Falcarindiol was identified as the main active principle whereas the phenylpropanoids and lignans showed no activity.
| Original language | English |
|---|---|
| Pages (from-to) | 553-557 |
| Number of pages | 5 |
| Journal | Zeitschrift fur Naturforschung - Section C Journal of Biosciences |
| Volume | 58 |
| Issue number | 7-8 |
| DOIs | |
| Publication status | Published - 2003 |
| Externally published | Yes |
Austrian Fields of Science 2012
- 301204 Pharmacognosy
Keywords
- 1′-Angeloyloxymyristicin
- 1′-Hydroxymyristicin
- Antimicrobial Activity
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