Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

Gemma Navarro; Gelja Maiwald; Rudolf Haase; Andrey L. Rogach; Ernst Wagner; Conchita Tros de Ilarduya; Manfred Ogris

doi:10.1016/j.jconrel.2010.04.030

Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

Gemma Navarro
, Gelja Maiwald
, Rudolf Haase
, Andrey L. Rogach
, Ernst Wagner
, Conchita Tros de Ilarduya
, Manfred Ogris

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	99-105
Number of pages	7
Journal	Journal of Controlled Release
Volume	146
Issue number	1
DOIs	https://doi.org/10.1016/j.jconrel.2010.04.030
Publication status	Published - 17 Aug 2010
Externally published	Yes

Funding

This work was supported by FUN (University of Navarra Foundation), Government of Navarra (Department of Education) and Bancaja Foundation, the EC funded project GIANT, DFG SFB486 and SPP1230, and the DFG Excellence Cluster "Nanosystems Initiative Munich" (NIM). Melinda Kiss is gratefully acknowledged for technical assistance.

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Keywords

PAMAM dendrimer
Tumor targeting
CpG free plasmid
GENE DELIVERY
IN-VIVO
LINEAR POLYETHYLENIMINE
DNA COMPLEXES
VITRO
POLYPLEXES
VECTOR
LUNG
TRANSFECTION
DYNAMICS

Access to Document

10.1016/j.jconrel.2010.04.030

Cite this

@article{f858b035678c4f51804fec35cfb95b82,

title = "Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery",

keywords = "PAMAM dendrimer, Tumor targeting, CpG free plasmid, GENE DELIVERY, IN-VIVO, LINEAR POLYETHYLENIMINE, DNA COMPLEXES, VITRO, POLYPLEXES, VECTOR, LUNG, TRANSFECTION, DYNAMICS",

author = "Gemma Navarro and Gelja Maiwald and Rudolf Haase and Rogach, \{Andrey L.\} and Ernst Wagner and \{Tros de Ilarduya\}, Conchita and Manfred Ogris",

year = "2010",

month = aug,

day = "17",

doi = "10.1016/j.jconrel.2010.04.030",

language = "English",

volume = "146",

pages = "99--105",

journal = "Journal of Controlled Release",

issn = "0168-3659",

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TY - JOUR

T1 - Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

AU - Navarro, Gemma

AU - Maiwald, Gelja

AU - Haase, Rudolf

AU - Rogach, Andrey L.

AU - Wagner, Ernst

AU - Tros de Ilarduya, Conchita

AU - Ogris, Manfred

PY - 2010/8/17

Y1 - 2010/8/17

KW - PAMAM dendrimer

KW - Tumor targeting

KW - CpG free plasmid

KW - GENE DELIVERY

KW - IN-VIVO

KW - LINEAR POLYETHYLENIMINE

KW - DNA COMPLEXES

KW - VITRO

KW - POLYPLEXES

KW - VECTOR

KW - LUNG

KW - TRANSFECTION

KW - DYNAMICS

U2 - 10.1016/j.jconrel.2010.04.030

DO - 10.1016/j.jconrel.2010.04.030

M3 - Article

SN - 0168-3659

VL - 146

SP - 99

EP - 105

JO - Journal of Controlled Release

JF - Journal of Controlled Release

IS - 1

ER -

Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery

Funding

Austrian Fields of Science 2012

Keywords

Access to Document

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Cite this