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Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3

  • Alison Gardner
  • , Wei Wu
  • , Steven Thomson
  • , Eva-Maria Zangerl-Plessl
  • , Anna Stary-Weinzinger
  • , Michael C Sanguinetti (Corresponding author)

    Publications: Contribution to journalArticlePeer Reviewed

    Original languageEnglish
    Pages (from-to)437-450
    Number of pages14
    JournalMolecular Pharmacology
    Volume92
    Issue number4
    DOIs
    Publication statusPublished - Oct 2017

    Austrian Fields of Science 2012

    • 301206 Pharmacology

    Keywords

    • Animals
    • Dose-Response Relationship, Drug
    • Ether-A-Go-Go Potassium Channels
    • Ginsenosides
    • Humans
    • Ion Channel Gating
    • Protein Structure, Secondary
    • Xenopus laevis
    • Journal Article
    • DOMAIN
    • MECHANISM
    • DETERMINANTS
    • STOICHIOMETRY
    • INACTIVATION
    • ACTIVATOR
    • MUTATIONS
    • K+ CHANNEL
    • RESIDUES
    • POTASSIUM CHANNEL

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