N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine

Philipp Saiko; Maria Ozsvar-Kozma; Astrid Bernhaus; Margit Jaschke; Geraldine Graser; Andreas Lackner; Michael Grusch; Zsuzsanna Horvath; Sibylle Madlener; Georg Krupitza; Norbert Handler; Thomas Erker; Walter Jäger; Monika Fritzer-Szekeres; Thomas Szekeres

doi:10.3892/ijo.31.5.1261

N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine

Philipp Saiko, Maria Ozsvar-Kozma, Astrid Bernhaus, Margit Jaschke, Geraldine Graser, Andreas Lackner, Michael Grusch, Zsuzsanna Horvath, Sibylle Madlener, Georg Krupitza, Norbert Handler, Thomas Erker, Walter Jäger, Monika Fritzer-Szekeres, Thomas Szekeres

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	1261-1266
Number of pages	6
Journal	International Journal of Oncology
Volume	31
Issue number	5
DOIs	https://doi.org/10.3892/ijo.31.5.1261
Publication status	Published - Nov 2007

Austrian Fields of Science 2012

301207 Pharmaceutical chemistry

Keywords

resveratrol
N-hydroxy-N '-(3,4,5-trimethoxyphenyl)3,4,5-trimethoxybenzamidine
ribonucleotide reductase
arabinofuranosylcytosine
HL-60 human promyelocytic leukemia cells
synergistic combination effects
CHEMOPREVENTIVE AGENT RESVERATROL
ACUTE MYELOID-LEUKEMIA
ARABINOSYLCYTOSINE METABOLISM
CANCER CELLS
ARA-C
APOPTOSIS
GROWTH
PROLIFERATION
CYTARABINE
ACTIVATION

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Saiko, P., Ozsvar-Kozma, M., Bernhaus, A., Jaschke, M., Graser, G., Lackner, A., Grusch, M., Horvath, Z., Madlener, S., Krupitza, G., Handler, N., Erker, T., Jäger, W., Fritzer-Szekeres, M., & Szekeres, T. (2007). N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine. International Journal of Oncology, 31(5), 1261-1266. https://doi.org/10.3892/ijo.31.5.1261

Saiko, Philipp ; Ozsvar-Kozma, Maria ; Bernhaus, Astrid et al. / N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells : Synergistic antitumor activity with arabinofuranosylcytosine. In: International Journal of Oncology. 2007 ; Vol. 31, No. 5. pp. 1261-1266.

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title = "N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine",

keywords = "resveratrol, N-hydroxy-N '-(3,4,5-trimethoxyphenyl)3,4,5-trimethoxybenzamidine, ribonucleotide reductase, arabinofuranosylcytosine, HL-60 human promyelocytic leukemia cells, synergistic combination effects, CHEMOPREVENTIVE AGENT RESVERATROL, ACUTE MYELOID-LEUKEMIA, ARABINOSYLCYTOSINE METABOLISM, CANCER CELLS, ARA-C, APOPTOSIS, GROWTH, PROLIFERATION, CYTARABINE, ACTIVATION",

author = "Philipp Saiko and Maria Ozsvar-Kozma and Astrid Bernhaus and Margit Jaschke and Geraldine Graser and Andreas Lackner and Michael Grusch and Zsuzsanna Horvath and Sibylle Madlener and Georg Krupitza and Norbert Handler and Thomas Erker and Walter J{\"a}ger and Monika Fritzer-Szekeres and Thomas Szekeres",

year = "2007",

month = nov,

doi = "10.3892/ijo.31.5.1261",

language = "English",

volume = "31",

pages = "1261--1266",

journal = "International Journal of Oncology",

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Saiko, P, Ozsvar-Kozma, M, Bernhaus, A, Jaschke, M, Graser, G, Lackner, A, Grusch, M, Horvath, Z, Madlener, S, Krupitza, G, Handler, N, Erker, T, Jäger, W, Fritzer-Szekeres, M & Szekeres, T 2007, 'N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine', International Journal of Oncology, vol. 31, no. 5, pp. 1261-1266. https://doi.org/10.3892/ijo.31.5.1261

N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine. / Saiko, Philipp; Ozsvar-Kozma, Maria; Bernhaus, Astrid et al.
In: International Journal of Oncology, Vol. 31, No. 5, 11.2007, p. 1261-1266.

Publications: Contribution to journal › Article › Peer Reviewed

TY - JOUR

T1 - N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells

T2 - Synergistic antitumor activity with arabinofuranosylcytosine

AU - Saiko, Philipp

AU - Ozsvar-Kozma, Maria

AU - Bernhaus, Astrid

AU - Jaschke, Margit

AU - Graser, Geraldine

AU - Lackner, Andreas

AU - Grusch, Michael

AU - Horvath, Zsuzsanna

AU - Madlener, Sibylle

AU - Krupitza, Georg

AU - Handler, Norbert

AU - Erker, Thomas

AU - Jäger, Walter

AU - Fritzer-Szekeres, Monika

AU - Szekeres, Thomas

PY - 2007/11

Y1 - 2007/11

KW - resveratrol

KW - N-hydroxy-N '-(3,4,5-trimethoxyphenyl)3,4,5-trimethoxybenzamidine

KW - ribonucleotide reductase

KW - arabinofuranosylcytosine

KW - HL-60 human promyelocytic leukemia cells

KW - synergistic combination effects

KW - CHEMOPREVENTIVE AGENT RESVERATROL

KW - ACUTE MYELOID-LEUKEMIA

KW - ARABINOSYLCYTOSINE METABOLISM

KW - CANCER CELLS

KW - ARA-C

KW - APOPTOSIS

KW - GROWTH

KW - PROLIFERATION

KW - CYTARABINE

KW - ACTIVATION

U2 - 10.3892/ijo.31.5.1261

DO - 10.3892/ijo.31.5.1261

M3 - Article

SN - 1019-6439

VL - 31

SP - 1261

EP - 1266

JO - International Journal of Oncology

JF - International Journal of Oncology

IS - 5

ER -

Saiko P, Ozsvar-Kozma M, Bernhaus A, Jaschke M, Graser G, Lackner A et al. N-hydroxy-N '-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxybenzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: Synergistic antitumor activity with arabinofuranosylcytosine. International Journal of Oncology. 2007 Nov;31(5):1261-1266. doi: 10.3892/ijo.31.5.1261