One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function

Krzysztof Mikolajczyk; Mateusz Sikora; Cyril Hanus; Radoslaw Kaczmarek; Marcin Czerwinski

doi:10.1016/j.bbrc.2022.05.085

One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function

Krzysztof Mikolajczyk (Corresponding author)
, Mateusz Sikora
, Cyril Hanus
, Radoslaw Kaczmarek
, Marcin Czerwinski

Computational and Soft Matter Physics

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	36-41
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	617
DOIs	https://doi.org/10.1016/j.bbrc.2022.05.085
Publication status	Published - 20 Aug 2022

Funding

This project was supported by the Ministry of Education and Science of Poland "Diamentowy Grant" 0097/DIA/2017/46. MS is indebted to the Austrian Science Fund FWF (Schrodinger Fellowship, J4332-B28).

Austrian Fields of Science 2012

106006 Biophysics
103043 Computational physics
301402 Neurobiology

Keywords

Gb3/CD77 synthase
Glycosyltransferase
HEK293
N-glycan
P1PK blood group
Protein modeling
DYNAMICS
NOR
P1

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10.1016/j.bbrc.2022.05.085

Cite this

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title = "One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function",

keywords = "Gb3/CD77 synthase, Glycosyltransferase, HEK293, N-glycan, P1PK blood group, Protein modeling, DYNAMICS, NOR, P1",

author = "Krzysztof Mikolajczyk and Mateusz Sikora and Cyril Hanus and Radoslaw Kaczmarek and Marcin Czerwinski",

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One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function. / Mikolajczyk, Krzysztof (Corresponding author); Sikora, Mateusz; Hanus, Cyril et al.
In: Biochemical and Biophysical Research Communications, Vol. 617, 20.08.2022, p. 36-41.

Publications: Contribution to journal › Article › Peer Reviewed

TY - JOUR

T1 - One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function

AU - Mikolajczyk, Krzysztof

AU - Sikora, Mateusz

AU - Hanus, Cyril

AU - Kaczmarek, Radoslaw

AU - Czerwinski, Marcin

PY - 2022/8/20

Y1 - 2022/8/20

KW - Gb3/CD77 synthase

KW - Glycosyltransferase

KW - HEK293

KW - N-glycan

KW - P1PK blood group

KW - Protein modeling

KW - DYNAMICS

KW - NOR

KW - P1

UR - https://www.scopus.com/pages/publications/85131361742

U2 - 10.1016/j.bbrc.2022.05.085

DO - 10.1016/j.bbrc.2022.05.085

M3 - Article

SN - 0006-291X

VL - 617

SP - 36

EP - 41

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

ER -

One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function

Funding

Austrian Fields of Science 2012

Keywords

Access to Document

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Multiscale simulations of cell adhesion receptor clustering

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One of the two N-glycans on the human Gb3/CD77 synthase is essential for its activity and allosterically regulates its function

Funding

Austrian Fields of Science 2012

Keywords

Access to Document

Other files and links

Fingerprint

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Multiscale simulations of cell adhesion receptor clustering

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