Phylogenetic analysis of and oligonucleotide probe development for Eikelboom type 021N filamentous bacteria isolated from bulking activated sludge

Takahiro Kanagawa, Y Kamagata, Shinobu Aruga, Tetsuro Kohno, Matthias Horn, Michael Wagner

    Publications: Contribution to journalArticlePeer Reviewed

    Abstract

    Fifteen filamentous strains, morphologically classified as Eikelboom type 021N bacteria, were isolated from bulking activated sludges. Based on comparative 16S ribosomal DNA (rDNA) sequence analysis, all strains form a monophyletic cluster together with all recognized Thiothrix species (88.3 to 98.7% 16S rDNA sequence similarity) within the gamma-subclass of Proteobacteria. The investigated Eikelboom type 021N isolates were subdivided into three distinct groups (I to III) demonstrating a previously unrecognized genetic diversity hidden behind the uniform morphology of the filaments. For in situ detection of these bacteria, 16S rRNA-targeted oligonucleotide probes specific for the entire Eikelboom type 021N-Thiothrix cluster and the Eikelboom type 021N groups I, II, and III, respectively, were designed, evaluated, and successfully applied in activated sludge.
    Original languageEnglish
    Pages (from-to)5043-5052
    Number of pages10
    JournalApplied and Environmental Microbiology
    Volume66
    Issue number11
    Publication statusPublished - 2000

    Austrian Fields of Science 2012

    • 1060 Biology

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