PI by NMR: Probing CH–π Interactions in Protein–Ligand Complexes by NMR Spectroscopy

Gerald Platzer (Corresponding author), Moriz Mayer (Corresponding author), Andreas Beier, Sven Brüschweiler, Julian E. Fuchs, Harald Engelhardt, Leonhard Geist, Gerd Bader, Julia Schoerghuber, Roman Lichtenecker, Bernhard Wolkerstorfer, Dirk Kessler, Darryl B. McConnell, Robert Konrat

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)14861-14868
Number of pages8
JournalAngewandte Chemie (International Edition)
Volume59
Issue number35
DOIs
Publication statusPublished - 24 Aug 2020

Austrian Fields of Science 2012

  • 104026 Spectroscopy
  • 104015 Organic chemistry
  • 301305 Medical chemistry
  • 106041 Structural biology

Keywords

  • CH-pi interactions
  • medicinal chemistry
  • NMR spectroscopy
  • protein-ligand interactions
  • structure-based drug design
  • CH/PI-INTERACTION
  • RING-CURRENT
  • CHEMICAL-SHIFTS
  • HYDROGEN-BONDS
  • AROMATIC RINGS
  • BENZENE DIMER
  • BINDING
  • RECOGNITION
  • MAGNITUDE
  • DYNAMICS
  • protein–ligand interactions
  • CH–π interactions

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