Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl)quinic acid from Podospermum laciniatum (Asteraceae)

Christian Zidorn; Bent O. Petersen; Vedrana Udovičić; Thomas O. Larsen; Jens Duus; Judith M. Rollinger; Karl Hans Ongania; Ernst P. Ellmerer; Hermann Stuppner

doi:10.1016/j.tetlet.2004.12.118

Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl)quinic acid from Podospermum laciniatum (Asteraceae)

Christian Zidorn
, Bent O. Petersen
, Vedrana Udovičić
, Thomas O. Larsen
, Jens Duus
, Judith M. Rollinger
, Karl Hans Ongania
, Ernst P. Ellmerer
, Hermann Stuppner

Publications: Contribution to journal › Article › Peer Reviewed

Abstract

A phytochemical investigation of Podospermum laciniatum (L.) DC. (Asteraceae) yielded the new quinic acid derivative podospermic acid (1,3,5-tridihydrocaffeoylquinic acid), which was named after the genus it was isolated from. The structure was established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy. Podospermic acid is the first naturally occurring dihydrocaffeoylquinic acid derivative. The chemosystematic impact and the radical scavenging activity of the new compound are discussed briefly.

Original language	English
Pages (from-to)	1291-1294
Number of pages	4
Journal	Tetrahedron Letters
Volume	46
Issue number	8
DOIs	https://doi.org/10.1016/j.tetlet.2004.12.118
Publication status	Published - 21 Feb 2005
Externally published	Yes

Funding

The authors wish to thank R. Spitaler (Institut für Pharmazie, Innsbruck) for helping collect and K. Pagitz (Institut für Botanik, Innsbruck) for helping to determine the plant material. This work was supported by the Fonds zur Förderung der wissenschaftlichen Forschung (FWF, project P12695-BIO). The spectra at 800 MHz were obtained on the Varian Unity Inova spectrometer of the Danish Instrument Center for NMR Spectroscopy of Biological Macromolecules.

Austrian Fields of Science 2012

301204 Pharmacognosy

Keywords

Asteraceae
Natural products
Phenolics
Podospermum
Subtribe Scorzonerinae
Tribe Lactuceae

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10.1016/j.tetlet.2004.12.118

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title = "Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl)quinic acid from Podospermum laciniatum (Asteraceae)",

abstract = "A phytochemical investigation of Podospermum laciniatum (L.) DC. (Asteraceae) yielded the new quinic acid derivative podospermic acid (1,3,5-tridihydrocaffeoylquinic acid), which was named after the genus it was isolated from. The structure was established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy. Podospermic acid is the first naturally occurring dihydrocaffeoylquinic acid derivative. The chemosystematic impact and the radical scavenging activity of the new compound are discussed briefly.",

keywords = "Asteraceae, Natural products, Phenolics, Podospermum, Subtribe Scorzonerinae, Tribe Lactuceae",

author = "Christian Zidorn and Petersen, \{Bent O.\} and Vedrana Udovi{\v c}i{\'c} and Larsen, \{Thomas O.\} and Jens Duus and Rollinger, \{Judith M.\} and Ongania, \{Karl Hans\} and Ellmerer, \{Ernst P.\} and Hermann Stuppner",

note = "Funding Information: The authors wish to thank R. Spitaler (Institut f{\"u}r Pharmazie, Innsbruck) for helping collect and K. Pagitz (Institut f{\"u}r Botanik, Innsbruck) for helping to determine the plant material. This work was supported by the Fonds zur F{\"o}rderung der wissenschaftlichen Forschung (FWF, project P12695-BIO). The spectra at 800 MHz were obtained on the Varian Unity Inova spectrometer of the Danish Instrument Center for NMR Spectroscopy of Biological Macromolecules. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2005",

month = feb,

day = "21",

doi = "10.1016/j.tetlet.2004.12.118",

language = "English",

volume = "46",

pages = "1291--1294",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

number = "8",

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AU - Zidorn, Christian

AU - Petersen, Bent O.

AU - Udovičić, Vedrana

AU - Larsen, Thomas O.

AU - Duus, Jens

AU - Rollinger, Judith M.

AU - Ongania, Karl Hans

AU - Ellmerer, Ernst P.

AU - Stuppner, Hermann

N1 - Funding Information: The authors wish to thank R. Spitaler (Institut für Pharmazie, Innsbruck) for helping collect and K. Pagitz (Institut für Botanik, Innsbruck) for helping to determine the plant material. This work was supported by the Fonds zur Förderung der wissenschaftlichen Forschung (FWF, project P12695-BIO). The spectra at 800 MHz were obtained on the Varian Unity Inova spectrometer of the Danish Instrument Center for NMR Spectroscopy of Biological Macromolecules. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2005/2/21

Y1 - 2005/2/21

N2 - A phytochemical investigation of Podospermum laciniatum (L.) DC. (Asteraceae) yielded the new quinic acid derivative podospermic acid (1,3,5-tridihydrocaffeoylquinic acid), which was named after the genus it was isolated from. The structure was established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy. Podospermic acid is the first naturally occurring dihydrocaffeoylquinic acid derivative. The chemosystematic impact and the radical scavenging activity of the new compound are discussed briefly.

AB - A phytochemical investigation of Podospermum laciniatum (L.) DC. (Asteraceae) yielded the new quinic acid derivative podospermic acid (1,3,5-tridihydrocaffeoylquinic acid), which was named after the genus it was isolated from. The structure was established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy. Podospermic acid is the first naturally occurring dihydrocaffeoylquinic acid derivative. The chemosystematic impact and the radical scavenging activity of the new compound are discussed briefly.

KW - Asteraceae

KW - Natural products

KW - Phenolics

KW - Podospermum

KW - Subtribe Scorzonerinae

KW - Tribe Lactuceae

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DO - 10.1016/j.tetlet.2004.12.118

M3 - Article

AN - SCOPUS:13244255477

SN - 0040-4039

VL - 46

SP - 1291

EP - 1294

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 8

ER -

Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl)quinic acid from Podospermum laciniatum (Asteraceae)

Abstract

Funding

Austrian Fields of Science 2012

Keywords

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