Probing the structure-function relationship of polyene macrolides: Engineered biosynthesis of soluble nystatin analogues

SEF Borgos, P Tsan, H Sletta, TE Ellingsen, JM Lancelin, SB Zotchev

    Publications: Contribution to journalArticlePeer Reviewed

    Original languageEnglish
    Pages (from-to)2431-2439
    Number of pages9
    JournalJournal of Medicinal Chemistry
    Volume49
    Issue number8
    DOIs
    Publication statusPublished - 20 Apr 2006

    Austrian Fields of Science 2012

    • 106022 Microbiology
    • 106013 Genetics
    • 106002 Biochemistry
    • 301204 Pharmacognosy

    Keywords

    • FATTY-ACID SYNTHASE
    • NOURSEI ATCC 11455
    • STREPTOMYCES-NOURSEI
    • POLYKETIDE SYNTHASE
    • ESCHERICHIA-COLI
    • AMPHOTERICIN-B
    • GENE-CLUSTER
    • SACCHAROPOLYSPORA-ERYTHRAEA
    • ANTIBIOTIC BIOSYNTHESIS
    • SENSITIVITY IMPROVEMENT

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