Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

Bjoern Bielec; Isabella Poetsch; Esra Ahmed; Petra Heffeter; Bernhard K. Keppler; Christian R. Kowol

doi:10.3390/molecules25051149

Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

Bjoern Bielec
, Isabella Poetsch
, Esra Ahmed
, Petra Heffeter
, Bernhard K. Keppler
, Christian R. Kowol (Corresponding author)

Department of Inorganic Chemistry

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	1149
Number of pages	18
Journal	Molecules
Volume	25
Issue number	5
DOIs	https://doi.org/10.3390/molecules25051149
Publication status	Published - 4 Mar 2020

Funding

This research was funded by the Austrian Science Fund (FWF), grant number P28853, to C.R.K.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Austrian Fields of Science 2012

301904 Cancer research
106002 Biochemistry
106023 Molecular biology

Keywords

anticancer
tyrosine kinase inhibitors
crizotinib
prodrugs
boronic acid
CELL LUNG-CANCER
DOCKING
Crizotinib
Prodrugs
Boronic acid
Anticancer
Tyrosine kinase inhibitors

Access to Document

10.3390/molecules25051149Licence: CC BY 4.0

https://phaidra.univie.ac.at/o:1230008Licence: CC BY 4.0

Cite this

@article{cf76172ac6d9454bbf355db2d2c3093d,

title = "Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib",

keywords = "anticancer, tyrosine kinase inhibitors, crizotinib, prodrugs, boronic acid, CELL LUNG-CANCER, DOCKING, Crizotinib, Prodrugs, Boronic acid, Anticancer, Tyrosine kinase inhibitors",

author = "Bjoern Bielec and Isabella Poetsch and Esra Ahmed and Petra Heffeter and Keppler, \{Bernhard K.\} and Kowol, \{Christian R.\}",

note = "Publisher Copyright: {\textcopyright} 2020 by the authors.",

year = "2020",

month = mar,

day = "4",

doi = "10.3390/molecules25051149",

language = "English",

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journal = "Molecules",

issn = "1420-3049",

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T1 - Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

AU - Bielec, Bjoern

AU - Poetsch, Isabella

AU - Ahmed, Esra

AU - Heffeter, Petra

AU - Keppler, Bernhard K.

AU - Kowol, Christian R.

PY - 2020/3/4

Y1 - 2020/3/4

KW - anticancer

KW - tyrosine kinase inhibitors

KW - crizotinib

KW - prodrugs

KW - boronic acid

KW - CELL LUNG-CANCER

KW - DOCKING

KW - Crizotinib

KW - Prodrugs

KW - Boronic acid

KW - Anticancer

KW - Tyrosine kinase inhibitors

UR - https://www.scopus.com/pages/publications/85081266627

U2 - 10.3390/molecules25051149

DO - 10.3390/molecules25051149

M3 - Article

SN - 1420-3049

VL - 25

JO - Molecules

JF - Molecules

IS - 5

M1 - 1149

ER -

Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

Funding

UN SDGs

Austrian Fields of Science 2012

Keywords

Access to Document

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