Robust eco-friendly protocol for the preparation of gamma-hydroxy-alpha,beta-acetylenic esters by sequential one-pot elimination-addition of 2-bromoacrylates to aldehydes promoted by LTMP in 2-MeTHF

Vittorio Pace (Corresponding author), Laura Castoldi, Andres R. Alcantara, Wolfgang Holzer

    Publications: Contribution to journalArticlePeer Reviewed

    Original languageEnglish
    Pages (from-to)1859-1863
    Number of pages5
    JournalGreen Chemistry
    Volume14
    Issue number7
    DOIs
    Publication statusPublished - 2012

    Austrian Fields of Science 2012

    • 301207 Pharmaceutical chemistry

    Keywords

    • HIGHLY ENANTIOSELECTIVE SYNTHESIS
    • PHOSPHINE-PHOSPHITE LIGANDS
    • PROPARGYLIC ALCOHOLS
    • GRIGNARD-REAGENTS
    • HEXAMETHYLPHOSPHORAMIDE
    • 2-METHYLTETRAHYDROFURAN
    • CONVERSION
    • SOLVENT
    • MILD
    • 1,4-ADDITION

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