Single Posttranslational Modifications in the Central Repeat Domains of Tau4 Impact its Aggregation and Tubulin Binding

Doris Ellmer, Manuel Brehs, Mahmood Haj-Yahya, Hilal A. Lashuel, Christian F. W. Becker (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)1616-1620
Number of pages5
JournalAngewandte Chemie (International Edition)
Volume58
Issue number6
DOIs
Publication statusPublished - 4 Feb 2019

Austrian Fields of Science 2012

  • 104004 Chemical biology

Keywords

  • neurodegeneration
  • protein aggregation
  • protein modifications
  • protein semisynthesis
  • Tau protein
  • PAIRED HELICAL FILAMENTS
  • ALZHEIMERS-DISEASE
  • PROTEIN-TAU
  • PHOSPHORYLATION
  • ACETYLATION
  • GLYCATION
  • ISOFORMS
  • NEURODEGENERATION
  • COMPONENT
  • PATTERN

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