SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

Matthias Muhar; Anja Ebert; Tobias Neumann; Christian Umkehrer; Julian Jude; Corinna Wieshofer; Philipp Rescheneder; Jesse J Lipp; Veronika A Herzog; Brian Reichholf; David A Cisneros; Thomas Hoffmann; Moritz F Schlapansky; Pooja Bhat; Arndt von Haeseler; Thomas Köcher; Anna C Obenauf; Johannes Popow; Stefan L Ameres; Johannes Zuber

doi:10.1126/science.aao2793

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

Matthias Muhar, Anja Ebert, Tobias Neumann, Christian Umkehrer, Julian Jude, Corinna Wieshofer, Philipp Rescheneder, Jesse J Lipp, Veronika A Herzog, Brian Reichholf, David A Cisneros, Thomas Hoffmann, Moritz F Schlapansky, Pooja Bhat, Arndt von Haeseler, Thomas Köcher, Anna C Obenauf, Johannes Popow, Stefan L Ameres, Johannes Zuber

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Pages (from-to)	800-805
Number of pages	6
Journal	Science
Volume	360
Issue number	6390
DOIs	https://doi.org/10.1126/science.aao2793
Publication status	Published - 2018

Austrian Fields of Science 2012

106005 Bioinformatics
106013 Genetics
301904 Cancer research

Keywords

TRANSCRIPTION ELONGATION
C-MYC
SELECTIVE-INHIBITION
SUPER-ENHANCERS
HUMAN GENOME
STEM-CELLS
LEUKEMIA
CANCER
RNA
RECRUITMENT

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1126/science.aao2793

Cite this

Muhar, M., Ebert, A., Neumann, T., Umkehrer, C., Jude, J., Wieshofer, C., Rescheneder, P., Lipp, J. J., Herzog, V. A., Reichholf, B., Cisneros, D. A., Hoffmann, T., Schlapansky, M. F., Bhat, P., von Haeseler, A., Köcher, T., Obenauf, A. C., Popow, J., Ameres, S. L., & Zuber, J. (2018). SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science, 360(6390), 800-805. https://doi.org/10.1126/science.aao2793

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title = "SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis",

keywords = "TRANSCRIPTION ELONGATION, C-MYC, SELECTIVE-INHIBITION, SUPER-ENHANCERS, HUMAN GENOME, STEM-CELLS, LEUKEMIA, CANCER, RNA, RECRUITMENT",

author = "Matthias Muhar and Anja Ebert and Tobias Neumann and Christian Umkehrer and Julian Jude and Corinna Wieshofer and Philipp Rescheneder and Lipp, {Jesse J} and Herzog, {Veronika A} and Brian Reichholf and Cisneros, {David A} and Thomas Hoffmann and Schlapansky, {Moritz F} and Pooja Bhat and {von Haeseler}, Arndt and Thomas K{\"o}cher and Obenauf, {Anna C} and Johannes Popow and Ameres, {Stefan L} and Johannes Zuber",

year = "2018",

doi = "10.1126/science.aao2793",

language = "English",

volume = "360",

pages = "800--805",

journal = "Science",

issn = "0036-8075",

publisher = "AMER ASSOC ADVANCEMENT SCIENCE",

number = "6390",

}

Muhar, M, Ebert, A, Neumann, T, Umkehrer, C, Jude, J, Wieshofer, C, Rescheneder, P, Lipp, JJ, Herzog, VA, Reichholf, B, Cisneros, DA, Hoffmann, T, Schlapansky, MF, Bhat, P, von Haeseler, A, Köcher, T, Obenauf, AC, Popow, J, Ameres, SL & Zuber, J 2018, 'SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis', Science, vol. 360, no. 6390, pp. 800-805. https://doi.org/10.1126/science.aao2793

TY - JOUR

T1 - SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

AU - Muhar, Matthias

AU - Ebert, Anja

AU - Neumann, Tobias

AU - Umkehrer, Christian

AU - Jude, Julian

AU - Wieshofer, Corinna

AU - Rescheneder, Philipp

AU - Lipp, Jesse J

AU - Herzog, Veronika A

AU - Reichholf, Brian

AU - Cisneros, David A

AU - Hoffmann, Thomas

AU - Schlapansky, Moritz F

AU - Bhat, Pooja

AU - von Haeseler, Arndt

AU - Köcher, Thomas

AU - Obenauf, Anna C

AU - Popow, Johannes

AU - Ameres, Stefan L

AU - Zuber, Johannes

PY - 2018

Y1 - 2018

KW - TRANSCRIPTION ELONGATION

KW - C-MYC

KW - SELECTIVE-INHIBITION

KW - SUPER-ENHANCERS

KW - HUMAN GENOME

KW - STEM-CELLS

KW - LEUKEMIA

KW - CANCER

KW - RNA

KW - RECRUITMENT

UR - http://www.scopus.com/inward/record.url?scp=85045136188&partnerID=8YFLogxK

U2 - 10.1126/science.aao2793

DO - 10.1126/science.aao2793

M3 - Article

C2 - 29622725

SN - 0036-8075

VL - 360

SP - 800

EP - 805

JO - Science

JF - Science

IS - 6390

ER -

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

Austrian Fields of Science 2012

Keywords

UN SDGs

Access to Document

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