Synthesis of ferrocenylglucose phosphonite and bisphosphinite: Pd(II) and Pt(II) complexes, Pd-catalyzed allylic alkylation

The synthesis and characterization of the new phosphorus containing ligands and the corresponding Pd(II) and Pt(II) complexes are reported. The molecular structure of 4,6-bis-O-(diphenylphosphino)-2,3-(ferrocene-1,1'-dicarbonyl)-O- methyl-a-D-glucopyranoside was determined by X-ray diffraction methods. The new ligands show good activity (90%) and moderate stereoselectivity (39% ee) in the Pd-catalyzed enantioselective allylic alkylation. Π2002 Elsevier Science Ltd. All rights reserved.