Systemic Image-Guided Liver Cancer Radiovirotherapy Using Dendrimer-Coated Adenovirus Encoding the Sodium Iodide Symporter as Theranostic Gene

Geoffrey K. Gruenwald, Alexandra Vetter, Kathrin Klutz, Michael J. Willhauck, Nathalie Schwenk, Reingard Senekowitsch-Schmidtke, Markus Schwaiger, Christian Zach, Ernst Wagner, Burkhard Goeke, Per S. Holm, Manfred Ogris, Christine Spitzweg

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)1450-1457
Number of pages8
JournalThe Journal of Nuclear Medicine
Volume54
Issue number8
DOIs
Publication statusPublished - Aug 2013
Externally publishedYes

Austrian Fields of Science 2012

  • 301207 Pharmaceutical chemistry

Keywords

  • adenovirus serotype 5
  • PAMAM dendrimer
  • sodium iodide symporter (NIS)
  • radiovirotherapy
  • gene therapy
  • CONDITIONALLY REPLICATING ADENOVIRUS
  • PROSTATE-CANCER
  • TARGETED RADIOTHERAPY
  • MULTIPLE-MYELOMA
  • RADIOIODINE THERAPY
  • NONVIRAL DELIVERY
  • NA/I SYMPORTER
  • EXPRESSION
  • VECTORS
  • CELLS

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