The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia

Teresa Mortera Blanco, Athanasios Mantalaris, Alexander Bismarck, Nicki Panoskaltsis (Corresponding author)

Publications: Contribution to journalArticlePeer Reviewed

Original languageEnglish
Pages (from-to)2243-2251
Number of pages9
JournalBiomaterials
Volume31
Issue number8
DOIs
Publication statusPublished - Mar 2010
Externally publishedYes

Funding

This work was funded by the Richard Thomas Leukaemia Fund, the Lady Tata Memorial Trust, and the Northwick Park Hospital Leukaemia Research Trust Fund. The authors are grateful to Christine Bateman and her team (Histopathology, Department of Pathology, Northwick Park and St. Mark's Hospital, London) for assistance with the sectioning of the scaffolds and the Tissue Engineering and Regenerative Medicine Centre, Chelsea & Westminster Campus, Imperial College London for providing facilities for the paraffin embedding.

Austrian Fields of Science 2012

  • 205019 Material sciences

Keywords

  • Three-dimensional culture
  • Scaffold
  • Leukaemia culture
  • Haematopoiesis
  • CHRONIC MYELOGENOUS LEUKEMIA
  • HEMATOPOIETIC-STEM-CELL
  • SURFACE MODIFICATION
  • SELF-RENEWAL
  • MARROW
  • GROWTH
  • PROLIFERATION
  • ADHESION
  • MAINTENANCE
  • CONSTRUCTS

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