Timescales of self-healing in human bone tissue and polymeric ionic liquids

Johanna Akbarzadeh; Stephan Puchegger; Anja Stojanovic; Helmut O. K. Kirchner; Wolfgang H. Binder; Sigrid Bernstorff; Peter Zioupos; Herwig Peterlik

doi:10.1680/bbn.14.00007

Timescales of self-healing in human bone tissue and polymeric ionic liquids

Johanna Akbarzadeh, Stephan Puchegger, Anja Stojanovic, Helmut O. K. Kirchner, Wolfgang H. Binder, Sigrid Bernstorff, Peter Zioupos, Herwig Peterlik (Corresponding author)

Publications: Contribution to journal › Article › Peer Reviewed

Abstract

Strain (stress-free) relaxation in mechanically prestrained bone has a time constant of 75 s. It occurs by a reorganization of the proteoglycan-glycoprotein matrix between collagen fibers, which requires ionic interactions. Dissolving and relinking the ionic bonds is thus an important tool of nature to enable plastic deformation and to develop self-healing tissues. A way to transfer this approach to technical materials is the attachment of ionic end groups to polymeric chains. In these classes of materials, the so-called polymeric ionic liquids, structural recovery of thermally disorganized material is observed. A time constant between minutes and a week could be achieved, also by ionic rearrangement. The same mechanism, rearrangement of ionic bonds, can lead to vastly different relaxation times when the ionic interaction is varied by exchange of the cationic end groups or the anions.

Original language	English
Pages (from-to)	123-130
Number of pages	8
Journal	Bioinspired, Biomimetic and Nanobiomaterials
Volume	3
Issue number	3
DOIs	https://doi.org/10.1680/bbn.14.00007
Publication status	Published - 1 Sept 2014

Funding

JA and HP acknowledge the support from the Austrian Science Funds (FWF), proj. nr. I449 and the German Research Foundation (DFG), proj. nr. PE 1732/1-2. PZ acknowledges the support provided by EPSRC (UK) under the 'Point-of-Care High Accuracy Fracture Risk Prediction' EP/K020196/1 grant. AS and WHB acknowledge the support from the German Research Foundation (DFG), proj. nr. BI 1337/8-1 within the SPP 1568 ('Design and Generic Principles of Self-Healing Materials').

Austrian Fields of Science 2012

103015 Condensed matter
103018 Materials physics

Keywords

biomimetic material
click chemistry
macromolecule
mechanical properties
nanobioscience
nanostructures
polymer functionalization
self-healing
HUMAN CORTICAL BONE
VISCOELASTIC PROPERTIES
IN-VIVO
BIOMECHANICAL PROPERTIES
MECHANICAL-PROPERTIES
SACRIFICIAL BONDS
HIDDEN LENGTH
STRAIN-RATE
COLLAGEN
FRACTURE
Polymer functionalization
Mechanical properties
Self-healing
Nanobioscience
Biomimetic material
Click chemistry

Access to Document

10.1680/bbn.14.00007

Cite this

@article{ffeb065baa294fee81c86207397a2ad9,

title = "Timescales of self-healing in human bone tissue and polymeric ionic liquids",

abstract = "Strain (stress-free) relaxation in mechanically prestrained bone has a time constant of 75 s. It occurs by a reorganization of the proteoglycan-glycoprotein matrix between collagen fibers, which requires ionic interactions. Dissolving and relinking the ionic bonds is thus an important tool of nature to enable plastic deformation and to develop self-healing tissues. A way to transfer this approach to technical materials is the attachment of ionic end groups to polymeric chains. In these classes of materials, the so-called polymeric ionic liquids, structural recovery of thermally disorganized material is observed. A time constant between minutes and a week could be achieved, also by ionic rearrangement. The same mechanism, rearrangement of ionic bonds, can lead to vastly different relaxation times when the ionic interaction is varied by exchange of the cationic end groups or the anions.",

keywords = "biomimetic material, click chemistry, macromolecule, mechanical properties, nanobioscience, nanostructures, polymer functionalization, self-healing, HUMAN CORTICAL BONE, VISCOELASTIC PROPERTIES, IN-VIVO, BIOMECHANICAL PROPERTIES, MECHANICAL-PROPERTIES, SACRIFICIAL BONDS, HIDDEN LENGTH, STRAIN-RATE, COLLAGEN, FRACTURE, Polymer functionalization, Mechanical properties, Self-healing, Nanobioscience, Biomimetic material, Click chemistry",

author = "Johanna Akbarzadeh and Stephan Puchegger and Anja Stojanovic and Kirchner, \{Helmut O. K.\} and Binder, \{Wolfgang H.\} and Sigrid Bernstorff and Peter Zioupos and Herwig Peterlik",

year = "2014",

month = sep,

day = "1",

doi = "10.1680/bbn.14.00007",

language = "English",

volume = "3",

pages = "123--130",

journal = "Bioinspired, Biomimetic and Nanobiomaterials",

issn = "2045-9858",

number = "3",

}

TY - JOUR

T1 - Timescales of self-healing in human bone tissue and polymeric ionic liquids

AU - Akbarzadeh, Johanna

AU - Puchegger, Stephan

AU - Stojanovic, Anja

AU - Kirchner, Helmut O. K.

AU - Binder, Wolfgang H.

AU - Bernstorff, Sigrid

AU - Zioupos, Peter

AU - Peterlik, Herwig

PY - 2014/9/1

Y1 - 2014/9/1

N2 - Strain (stress-free) relaxation in mechanically prestrained bone has a time constant of 75 s. It occurs by a reorganization of the proteoglycan-glycoprotein matrix between collagen fibers, which requires ionic interactions. Dissolving and relinking the ionic bonds is thus an important tool of nature to enable plastic deformation and to develop self-healing tissues. A way to transfer this approach to technical materials is the attachment of ionic end groups to polymeric chains. In these classes of materials, the so-called polymeric ionic liquids, structural recovery of thermally disorganized material is observed. A time constant between minutes and a week could be achieved, also by ionic rearrangement. The same mechanism, rearrangement of ionic bonds, can lead to vastly different relaxation times when the ionic interaction is varied by exchange of the cationic end groups or the anions.

AB - Strain (stress-free) relaxation in mechanically prestrained bone has a time constant of 75 s. It occurs by a reorganization of the proteoglycan-glycoprotein matrix between collagen fibers, which requires ionic interactions. Dissolving and relinking the ionic bonds is thus an important tool of nature to enable plastic deformation and to develop self-healing tissues. A way to transfer this approach to technical materials is the attachment of ionic end groups to polymeric chains. In these classes of materials, the so-called polymeric ionic liquids, structural recovery of thermally disorganized material is observed. A time constant between minutes and a week could be achieved, also by ionic rearrangement. The same mechanism, rearrangement of ionic bonds, can lead to vastly different relaxation times when the ionic interaction is varied by exchange of the cationic end groups or the anions.

KW - biomimetic material

KW - click chemistry

KW - macromolecule

KW - mechanical properties

KW - nanobioscience

KW - nanostructures

KW - polymer functionalization

KW - self-healing

KW - HUMAN CORTICAL BONE

KW - VISCOELASTIC PROPERTIES

KW - IN-VIVO

KW - BIOMECHANICAL PROPERTIES

KW - MECHANICAL-PROPERTIES

KW - SACRIFICIAL BONDS

KW - HIDDEN LENGTH

KW - STRAIN-RATE

KW - COLLAGEN

KW - FRACTURE

KW - Polymer functionalization

KW - Mechanical properties

KW - Self-healing

KW - Nanobioscience

KW - Biomimetic material

KW - Click chemistry

UR - https://www.scopus.com/pages/publications/84930190101

U2 - 10.1680/bbn.14.00007

DO - 10.1680/bbn.14.00007

M3 - Article

SN - 2045-9858

VL - 3

SP - 123

EP - 130

JO - Bioinspired, Biomimetic and Nanobiomaterials

JF - Bioinspired, Biomimetic and Nanobiomaterials

IS - 3

ER -

Timescales of self-healing in human bone tissue and polymeric ionic liquids

Abstract

Funding

Austrian Fields of Science 2012

Keywords

Access to Document

Other files and links

Fingerprint

Cite this