TY - JOUR
T1 - Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry
AU - Urpi-Sarda, Mireia
AU - Jauregui, Olga
AU - Lamuela-Raventos, Rosa M.
AU - Jäger, Walter
AU - Böhmdorfer, Michaela
AU - Covas, Maria-Isabel
AU - Andres-Lacueva, Cristina
N1 - Zeitschrift: Analytical Chemistry
DOI: 10.1021/ac0484272
Coden: ANCHA
Affiliations: Nutrition and Food Science Department, Pharmacy Faculty, University of Barcelona, 08028 Barcelona, Spain; Scientific and Technical Services, University of Barcelona, 08028 Barcelona, Spain; Institute of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria; Unitat de Lipids i Epidemiologia Cardiovascular de l'Institut Municipal d'Investigacio Medica, Barcelona, Spain
Source-File: MedPharmChemScopus_iso.csv
Import aus Scopus: 2-s2.0-18844372768
Importdatum: 22.11.2006 17:15:22
09.08.2007: Datenanforderung 1817 (Import Sachbearbeiter)
PY - 2005
Y1 - 2005
N2 - In this paper, a sensitive, precise, and selective analytical method has been developed for the identification and quantification of resveratrol metabolites in human low-density lipoprotein (IDL) after moderate consumption of red wine, using high-performance liquid chromatography electrospray in tandem mass spectrometry (LC-ESI-MS/ MS). From different extraction procedures tested, solid-phase extraction was selected to minimize matrix effects reaching the highest sensitivity. Standard calibration curves prepared in human LDL for trans-resveratrol were linear over a range of 0.44-438.59 pmol/mL. The accuracy and interassay precision of this LC-MS/MS assay for resveratrol showed a coefficient of variation of
AB - In this paper, a sensitive, precise, and selective analytical method has been developed for the identification and quantification of resveratrol metabolites in human low-density lipoprotein (IDL) after moderate consumption of red wine, using high-performance liquid chromatography electrospray in tandem mass spectrometry (LC-ESI-MS/ MS). From different extraction procedures tested, solid-phase extraction was selected to minimize matrix effects reaching the highest sensitivity. Standard calibration curves prepared in human LDL for trans-resveratrol were linear over a range of 0.44-438.59 pmol/mL. The accuracy and interassay precision of this LC-MS/MS assay for resveratrol showed a coefficient of variation of
M3 - Article
SN - 0003-2700
VL - 77
SP - 3149
EP - 3155
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 10
ER -