Water-soluble trithiolato-bridged dinuclear ruthenium(II) and osmium(II) arene complexes with bisphosphonate functionalized ligands as anticancer organometallics

Christoph A. Riedl; Alexander Rosner; Sophia Harringer; Philipp Salomon; Michaela Hejl; Michael A. Jakupec; Wolfgang Kandioller; Bernhard K. Keppler

doi:10.1016/j.jinorgbio.2021.111618

Water-soluble trithiolato-bridged dinuclear ruthenium(II) and osmium(II) arene complexes with bisphosphonate functionalized ligands as anticancer organometallics

Christoph A. Riedl, Alexander Rosner, Sophia Harringer, Philipp Salomon, Michaela Hejl, Michael A. Jakupec, Wolfgang Kandioller, Bernhard K. Keppler

Department of Inorganic Chemistry

Publications: Contribution to journal › Article › Peer Reviewed

Original language	English
Article number	111618
Number of pages	10
Journal	Journal of Inorganic Biochemistry
Volume	225
DOIs	https://doi.org/10.1016/j.jinorgbio.2021.111618
Publication status	Published - Dec 2021

Austrian Fields of Science 2012

104003 Inorganic chemistry
301904 Cancer research
106002 Biochemistry
106023 Molecular biology

Keywords

Organometallics
Ruthenium
Bisphosphonates
Targeting complexes
Anticancer
Hydroxy apatite binding
IN-VITRO
STRUCTURAL-CHARACTERIZATION
CYTOTOXICITY
NKP-1339
CYMENE
BONE

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jinorgbio.2021.111618

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Riedl, C. A., Rosner, A., Harringer, S., Salomon, P., Hejl, M., Jakupec, M. A., Kandioller, W., & Keppler, B. K. (2021). Water-soluble trithiolato-bridged dinuclear ruthenium(II) and osmium(II) arene complexes with bisphosphonate functionalized ligands as anticancer organometallics. Journal of Inorganic Biochemistry, 225, Article 111618. https://doi.org/10.1016/j.jinorgbio.2021.111618

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title = "Water-soluble trithiolato-bridged dinuclear ruthenium(II) and osmium(II) arene complexes with bisphosphonate functionalized ligands as anticancer organometallics",

keywords = "Organometallics, Ruthenium, Bisphosphonates, Targeting complexes, Anticancer, Hydroxy apatite binding, IN-VITRO, STRUCTURAL-CHARACTERIZATION, CYTOTOXICITY, NKP-1339, CYMENE, BONE",

author = "Riedl, {Christoph A.} and Alexander Rosner and Sophia Harringer and Philipp Salomon and Michaela Hejl and Jakupec, {Michael A.} and Wolfgang Kandioller and Keppler, {Bernhard K.}",

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year = "2021",

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doi = "10.1016/j.jinorgbio.2021.111618",

language = "English",

volume = "225",

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T1 - Water-soluble trithiolato-bridged dinuclear ruthenium(II) and osmium(II) arene complexes with bisphosphonate functionalized ligands as anticancer organometallics

AU - Riedl, Christoph A.

AU - Rosner, Alexander

AU - Harringer, Sophia

AU - Salomon, Philipp

AU - Hejl, Michaela

AU - Jakupec, Michael A.

AU - Kandioller, Wolfgang

AU - Keppler, Bernhard K.

PY - 2021/12

Y1 - 2021/12

KW - Organometallics

KW - Ruthenium

KW - Bisphosphonates

KW - Targeting complexes

KW - Anticancer

KW - Hydroxy apatite binding

KW - IN-VITRO

KW - STRUCTURAL-CHARACTERIZATION

KW - CYTOTOXICITY

KW - NKP-1339

KW - CYMENE

KW - BONE

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U2 - 10.1016/j.jinorgbio.2021.111618

DO - 10.1016/j.jinorgbio.2021.111618

M3 - Article

SN - 0162-0134

VL - 225

JO - Journal of Inorganic Biochemistry

JF - Journal of Inorganic Biochemistry

M1 - 111618

ER -

Water-soluble trithiolato-bridged dinuclear ruthenium(II) and osmium(II) arene complexes with bisphosphonate functionalized ligands as anticancer organometallics

Austrian Fields of Science 2012

Keywords

UN SDGs

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